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Sexual side effects: Loss of libido, impotence, testicular pain, testicle shrinkage, minor Peyronies (up to 10 degrees), penis pain, watery semen, Mental: Anxiety, insomnia, cognitive issues / brain fog. Accessibility Urology. Hcg I did 3000iu the first day then 250iu every other day for the four weeks. WebNeurogenesis was found to be reversed to normal 35 days after the last finasteride injection in male mice. Finally Cured From Post Finasteride Syndrome | Ray Peat Exp. For details, see text. I had a case of PFS that was a severe as it gets. (Read up on desensitization of Leydig Cells but don't get nervous at this plan) I'll never be without this stuff again. Finasteride I read the thing on Healthline where it says it doesn't raise testosterone in humans. What websites do you recommend visiting? Endocrinol. Taking a vitamin D supplement or getting moderate sun exposure on a daily basis could be helpful in restoring your bodys vitamin D levels. People with post finasteride syndrome can have increased food sensitivities, extreme mood swings, and low energy levels. Epub 2016 Jul 27. Recovered from Post Finasteride Syndrome! : r/tressless Retrograde ejaculation - Diagnosis and treatment - Mayo Clinic To date, the PFS Foundation has identified 104 such professionals who have published scientific findings and/or voiced opinions on causative links between finasteride and PFS. Some of these same doctors and researchers are also members of our Medical Professionals team, counseling PFS patients and their loved ones worldwide. If a high volume of sperm is found in your urine, you have retrograde ejaculation. That is 250IU, not a typo so youll mix your 5000iu HCG with 5CC water and take 1/4 CC intramuscular three times a week using an insulin needle Have you heard about it? Drugs generally won't help if retrograde ejaculation is due to surgery that causes permanent physical changes of your anatomy. Eliminate Trigger Foods. Finasteride oral tablet side effects: How to manage them WebA deterioration in the quality of life in affected individuals does not justify use of the drug. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? https://old.reddit.com/r/PostFinSyndrome/comments/ogcsjc/i_recovered_from_pfs_it_is_possible/. This procedure is usually done at the doctor's office. You're likely to start by seeing your family doctor. Thanks for visiting. Thats probably the worst part if you only read that forum youre pretty much going to feel hopeless. How is your dick being equivalent to your thumb not severe? 2012;97:306. In some cases, sperm can be recovered from the bladder, processed in the laboratory and used to inseminate your partner (intrauterine insemination). Therefore, I cut the pills in half (2.5mg) and toss the other half. The mods on that forum are fascists and dont allow the opinion and theory of other people. The presence of side effects during pharmacological treatment is unfortunately a quite common problem. To be honest, I think for the most part these recoveries werent PFS but rather hormonal imbalances. The number of men sharing their experience of Post-Finasteride Syndrome is steadily rising, painting a bleak picture of the life-shattering effects the drug can have. Make a donation. Anejaculation and retrograde ejaculation. sharing sensitive information, make sure youre on a federal Diagnosing and Reversing It", Is Post Finasteride Syndrome Real? With prostate cancer deaths overtaking that of breast cancer, it is important to know the side effects of finasteride. Brain Res Bull. I did the first day 300 mg clomid, then 100mg for the first two weeks, 50mg for the third week, and none for the forth week. Feeling dissociated and never present. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. Therefore, results here discussed indicate that PFS is an emerging clinical problem that needs to be further elucidated. I has numbness also. In such cases, treatment depends on the underlying cause. While they're often an effective treatment for retrograde ejaculation, medications can cause side effects or adverse reactions with other medications. Fertil Steril. Fertility and Sterility. These hippocampal neurogenesis changes after finasteride treatment have been linked to emotional behavior and this might contribute to the pathophysiology of affective disorders in humans. Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: Imipramine, an antidepressant. Waitttt wait wait. To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. If medication doesn't allow you to ejaculate semen, you will likely need infertility procedures known as assisted reproductive technology to get your partner pregnant. Im glad I did. After a bit over a week I decreased the dose to 10mg before bedtime and none in the afternoon. BONUS! Do you have diabetes or any other chronic health problems? Toxicol. This is a condition characterized by an enlarged prostate. https://forum.propeciahelp.com/t/my-story-yes-it-was-messy-and-yes-i-am-fine-now/5456. My doctor put me on 5mg daily cialis (+up to 15mg as needed before sex) clomiphene 25mg/daily anastrozole 1mg/week Addyi shockwave therapy ($3000 for 6 sessions) though this is definitely unnecessary and experimental. Post-finasteride syndrome - ScienceDirect When did you first begin having dry orgasms? Urologic Clinics of North America. Are there other possible causes for my symptoms or condition? Your doctor might also ask about any health problems, surgeries or cancers you've had and what medications you take. Essentially I took testosterone exogenously And I took hcg afterwards, https://old.reddit.com/r/PSSD/comments/7lfc1e/how_i_fixed_my_pssd/. Day 2 I noticed a bit more energy, but credited that to having a good night's sleep (did I mention this stuff helps you sleep better, too?) Int. Am I at risk of complications from this condition? Answer: Hormonal optimization while on finesteride there are many options including peptides, and HCG as well as clomid/arimidex. All rights reserved. https://old.reddit.com/r/steroids/comments/m5m7o9/help_steroids_for_pssd/gr0uhqj/. Althof HE, et al. And quite frankly, if you think big pharma doesn't have millions and millions of dollars wrapped up in trying to cover up just how severely finasteride has destroyed mens' lives, you're fooling yourself. 2013 Oct;10(10):2598-603. doi: 10.1111/jsm.12269. .FIYolDqalszTnjjNfThfT{max-width:256px;white-space:normal;text-align:center} I tried just about everything over 11 years. The supplement is making real changes in my body and mind, and it feels incredible. For each day that goes by, I get a day of surplus inventory. 2022 Jul 27;15(8):930. doi: 10.3390/ph15080930. Inability to concentrate. 2019;16 doi: 10.3390/ijerph16101726. ._2cHgYGbfV9EZMSThqLt2tx{margin-bottom:16px;border-radius:4px}._3Q7WCNdCi77r0_CKPoDSFY{width:75%;height:24px}._2wgLWvNKnhoJX3DUVT_3F-,._3Q7WCNdCi77r0_CKPoDSFY{background:var(--newCommunityTheme-field);background-size:200%;margin-bottom:16px;border-radius:4px}._2wgLWvNKnhoJX3DUVT_3F-{width:100%;height:46px} It looked like it had been around the world a few times. That's one of the mildest forms of PFS you can experience. -, Alkahtane A.A., Albasher G., Al-Sultan N.K., Alqahtani W.S., Alarifi S., Almeer R.S., Alghamdi J., Ali D., Alahmari A., Alkahtani S. Long-term treatment with finasteride induces apoptosis and pathological changes in female mice. https://forum.propeciahelp.com/t/i-think-im-healed-after-six-year-nightmare/35477. What Causes Hair Loss in Women? A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. Brain fog. I also tried testosterone treatment but it had almost no effect regardless of dosage. I only said everyone should read it, especially in light of the big new proviron recovery on the forum there. Public Health. The information on RealSelf is intended for educational purposes only. decreased libido * (sex drive) erectile dysfunction *. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). 5alpha-reductase; Androgenetic alopecia; Depression; Finasteride; Neuroactive steroids; Sexual dysfunction. Ive been doing this for over 2 years and have ZERO sexual side effects from the drug. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Book: Mayo Clinic Guide to Fertility and Conception. If your doctor thinks drugs you are taking might be affecting your ability to ejaculate normally, he or she might have you stop taking them for a period of time. Yeah, yeah. In addition, it has been also reported that persistent side effects may occur in some AGA patients. AR: androgen receptor; CSF: cerebrospinal fluid; MRI: magnetic resonance imaging; SRD5A2: 5 alpha reductase type 2 gene. Just bombarding their bodies with strong androgens. Indeed, some national agencies (e.g., Swedish Medical Products Agency, the Medicines and Healthcare Products Regulatory Agency of UK and the U.S. Food and Drug Administration) required to include multiple persistent side effects within the finasteride labels. Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: These medications help keep the bladder neck muscle closed during ejaculation. Next to no sensitivity in my genitals. Fertility and Sterility. It is available as a generic. I know how I feel and I know it's working. Post-Finasteride Syndrome: What is It? | hims I went from barely able to get an erection to having 4 very pleasurable orgasms on the third day. Btw, something weird happening on propeciahelp forums. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). Liu L, Zhao S, Li F, Li E, Kang R, Luo L, Luo J, Wan S, Zhao Z. J Sex Med. This report will provide you with the information you need to understand the current controversies, avoid common pitfalls, and work with your doctor to make informed choices about your prostate health. Adverse effects of common medications on male fertility. I understand not wanting to have a bunch of hack cures on their forum that dont really do anything or worse yet, make people worse, but at some point when theres a condition we dont know how to fix it seems like some trial and error wouldnt be the worst idea in the world. Ive seen this several times over there. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). At higher doses, finasteride (Proscar) can also treat benign prostatic hyperplasia (BPH). Finasteride oral tablet Being ready to answer your doctor's questions might save time to go over any points you want to spend more time on. The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. Best, Dr. Emer. Please enable it to take advantage of the complete set of features! I am not aware or scientific evidence that back this up at this time. I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. Post Finasteride Syndrome However, the side effects of a medication usually go away when you stop taking it. https://www.isarms.com/forums/threads/post-finasteride-syndrome.18175/. I have been prescribed a 2.5% DHT gel that is applied to the shoulders and forehead once a day. ._3Qx5bBCG_O8wVZee9J-KyJ{border-top:1px solid var(--newCommunityTheme-widgetColors-lineColor);margin-top:16px;padding-top:16px}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN{margin:0;padding:0}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:21px;display:-ms-flexbox;display:flex;-ms-flex-pack:justify;justify-content:space-between;-ms-flex-align:center;align-items:center;margin:8px 0}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ.QgBK4ECuqpeR2umRjYcP2{opacity:.4}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ label{font-size:12px;font-weight:500;line-height:16px;display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ label svg{fill:currentColor;height:20px;margin-right:4px;width:20px;-ms-flex:0 0 auto;flex:0 0 auto}._3Qx5bBCG_O8wVZee9J-KyJ ._4OtOUaGIjjp2cNJMUxme_{-ms-flex-pack:justify;justify-content:space-between}._3Qx5bBCG_O8wVZee9J-KyJ ._4OtOUaGIjjp2cNJMUxme_ svg{display:inline-block;height:12px;width:12px}._2b2iJtPCDQ6eKanYDf3Jho{-ms-flex:0 0 auto;flex:0 0 auto}._4OtOUaGIjjp2cNJMUxme_{padding:0 12px}._1ra1vBLrjtHjhYDZ_gOy8F{font-family:Noto Sans,Arial,sans-serif;font-size:12px;letter-spacing:unset;line-height:16px;text-transform:unset;--textColor:var(--newCommunityTheme-widgetColors-sidebarWidgetTextColor);--textColorHover:var(--newCommunityTheme-widgetColors-sidebarWidgetTextColorShaded80);font-size:10px;font-weight:700;letter-spacing:.5px;line-height:12px;text-transform:uppercase;color:var(--textColor);fill:var(--textColor);opacity:1}._1ra1vBLrjtHjhYDZ_gOy8F._2UlgIO1LIFVpT30ItAtPfb{--textColor:var(--newRedditTheme-widgetColors-sidebarWidgetTextColor);--textColorHover:var(--newRedditTheme-widgetColors-sidebarWidgetTextColorShaded80)}._1ra1vBLrjtHjhYDZ_gOy8F:active,._1ra1vBLrjtHjhYDZ_gOy8F:hover{color:var(--textColorHover);fill:var(--textColorHover)}._1ra1vBLrjtHjhYDZ_gOy8F:disabled,._1ra1vBLrjtHjhYDZ_gOy8F[data-disabled],._1ra1vBLrjtHjhYDZ_gOy8F[disabled]{opacity:.5;cursor:not-allowed}._3a4fkgD25f5G-b0Y8wVIBe{margin-right:8px} What was the article? 2008;35:211. When seeing your doctor for dry ejaculation the primary sign of retrograde ejaculation some basic questions to ask your doctor include: If you're trying to get your female partner pregnant, you might also want to ask: In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask additional questions during your appointment. Preparing a list of questions before your appointment can help you make the most of your time together. After numerous labs, I have determined that a dose of 2-3 mg is optimal for keeping my DHT within the normal range. Biomolecules. Before Bethesda, MD 20894, Web Policies Minoxidil is FDA approved for genetic hair loss - it does not help other conditions quite so much. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. I'm not a gym rat, I just make sure to walk 3-5 miles a day and do my best to watch what I eat (that's always been the case.) Hum. ._1QwShihKKlyRXyQSlqYaWW{height:16px;width:16px;vertical-align:bottom}._2X6EB3ZhEeXCh1eIVA64XM{margin-left:3px}._1jNPl3YUk6zbpLWdjaJT1r{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;padding:0 4px}._1jNPl3YUk6zbpLWdjaJT1r._39BEcWjOlYi1QGcJil6-yl{padding:0}._2hSecp_zkPm_s5ddV2htoj{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;margin-left:0;padding:0 4px}._2hSecp_zkPm_s5ddV2htoj._39BEcWjOlYi1QGcJil6-yl{padding:0}._1wzhGvvafQFOWAyA157okr{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;box-sizing:border-box;line-height:14px;padding:0 4px}._3BPVpMSn5b1vb1yTQuqCRH,._1wzhGvvafQFOWAyA157okr{display:inline-block;height:16px}._3BPVpMSn5b1vb1yTQuqCRH{background-color:var(--newRedditTheme-body);border-radius:50%;margin-left:5px;text-align:center;width:16px}._2cvySYWkqJfynvXFOpNc5L{height:10px;width:10px}.aJrgrewN9C8x1Fusdx4hh{padding:2px 8px}._1wj6zoMi6hRP5YhJ8nXWXE{font-size:14px;padding:7px 12px}._2VqfzH0dZ9dIl3XWNxs42y{border-radius:20px}._2VqfzH0dZ9dIl3XWNxs42y:hover{opacity:.85}._2VqfzH0dZ9dIl3XWNxs42y:active{transform:scale(.95)} Mehta A, et al. Many men with retrograde ejaculation are able to get their partners pregnant once they seek treatment. This site needs JavaScript to work properly. In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. If so, how long have you been trying to conceive? Create an account to follow your favorite communities and start taking part in conversations. This is to be expected because you are messing with a hormone (DHT) that is very important for sexual function. 2020 Jan;113(1):21-50. doi: 10.1016/j.fertnstert.2019.11.030. I'm Just 18 and I'm Losing my Hair. Finasteride Side Effects After Stopping: PFS & What Are They? Ive read theres on guy there who recoverd recently from HCG, very interesting. ._1EPynDYoibfs7nDggdH7Gq{margin-bottom:8px;position:relative}._1EPynDYoibfs7nDggdH7Gq._3-0c12FCnHoLz34dQVveax{max-height:63px;overflow:hidden}._1zPvgKHteTOub9dKkvrOl4{font-family:Noto Sans,Arial,sans-serif;font-size:14px;line-height:21px;font-weight:400;word-wrap:break-word}._1dp4_svQVkkuV143AIEKsf{-ms-flex-align:baseline;align-items:baseline;background-color:var(--newCommunityTheme-body);bottom:-2px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap;padding-left:2px;position:absolute;right:-8px}._5VBcBVybCfosCzMJlXzC3{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:21px;color:var(--newCommunityTheme-bodyText)}._3YNtuKT-Is6XUBvdluRTyI{position:relative;background-color:0;color:var(--newCommunityTheme-metaText);fill:var(--newCommunityTheme-metaText);border:0;padding:0 8px}._3YNtuKT-Is6XUBvdluRTyI:before{content:"";position:absolute;top:0;left:0;width:100%;height:100%;border-radius:9999px;background:var(--newCommunityTheme-metaText);opacity:0}._3YNtuKT-Is6XUBvdluRTyI:hover:before{opacity:.08}._3YNtuKT-Is6XUBvdluRTyI:focus{outline:none}._3YNtuKT-Is6XUBvdluRTyI:focus:before{opacity:.16}._3YNtuKT-Is6XUBvdluRTyI._2Z_0gYdq8Wr3FulRLZXC3e:before,._3YNtuKT-Is6XUBvdluRTyI:active:before{opacity:.24}._3YNtuKT-Is6XUBvdluRTyI:disabled,._3YNtuKT-Is6XUBvdluRTyI[data-disabled],._3YNtuKT-Is6XUBvdluRTyI[disabled]{cursor:not-allowed;filter:grayscale(1);background:none;color:var(--newCommunityTheme-metaTextAlpha50);fill:var(--newCommunityTheme-metaTextAlpha50)}._2ZTVnRPqdyKo1dA7Q7i4EL{transition:all .1s linear 0s}.k51Bu_pyEfHQF6AAhaKfS{transition:none}._2qi_L6gKnhyJ0ZxPmwbDFK{transition:all .1s linear 0s;display:block;background-color:var(--newCommunityTheme-field);border-radius:4px;padding:8px;margin-bottom:12px;margin-top:8px;border:1px solid var(--newCommunityTheme-canvas);cursor:pointer}._2qi_L6gKnhyJ0ZxPmwbDFK:focus{outline:none}._2qi_L6gKnhyJ0ZxPmwbDFK:hover{border:1px solid var(--newCommunityTheme-button)}._2qi_L6gKnhyJ0ZxPmwbDFK._3GG6tRGPPJiejLqt2AZfh4{transition:none;border:1px solid var(--newCommunityTheme-button)}.IzSmZckfdQu5YP9qCsdWO{cursor:pointer;transition:all .1s linear 0s}.IzSmZckfdQu5YP9qCsdWO ._1EPynDYoibfs7nDggdH7Gq{border:1px solid transparent;border-radius:4px;transition:all .1s linear 0s}.IzSmZckfdQu5YP9qCsdWO:hover ._1EPynDYoibfs7nDggdH7Gq{border:1px solid var(--newCommunityTheme-button);padding:4px}._1YvJWALkJ8iKZxUU53TeNO{font-size:12px;font-weight:700;line-height:16px;color:var(--newCommunityTheme-button)}._3adDzm8E3q64yWtEcs5XU7{display:-ms-flexbox;display:flex}._3adDzm8E3q64yWtEcs5XU7 ._3jyKpErOrdUDMh0RFq5V6f{-ms-flex:100%;flex:100%}._3adDzm8E3q64yWtEcs5XU7 .dqhlvajEe-qyxij0jNsi0{color:var(--newCommunityTheme-button)}._3adDzm8E3q64yWtEcs5XU7 ._12nHw-MGuz_r1dQx5YPM2v,._3adDzm8E3q64yWtEcs5XU7 .dqhlvajEe-qyxij0jNsi0{font-size:12px;font-weight:700;line-height:16px;cursor:pointer;-ms-flex-item-align:end;align-self:flex-end;-webkit-user-select:none;-ms-user-select:none;user-select:none}._3adDzm8E3q64yWtEcs5XU7 ._12nHw-MGuz_r1dQx5YPM2v{color:var(--newCommunityTheme-button);margin-right:8px;color:var(--newCommunityTheme-errorText)}._3zTJ9t4vNwm1NrIaZ35NS6{font-family:Noto Sans,Arial,sans-serif;font-size:14px;line-height:21px;font-weight:400;word-wrap:break-word;width:100%;padding:0;border:none;background-color:transparent;resize:none;outline:none;cursor:pointer;color:var(--newRedditTheme-bodyText)}._2JIiUcAdp9rIhjEbIjcuQ-{resize:none;cursor:auto}._2I2LpaEhGCzQ9inJMwliNO,._42Nh7O6pFcqnA6OZd3bOK{display:inline-block;margin-left:4px;vertical-align:middle}._42Nh7O6pFcqnA6OZd3bOK{fill:var(--newCommunityTheme-button);color:var(--newCommunityTheme-button);height:16px;width:16px;margin-bottom:2px}