Along with its needed effects, a medicine may cause some unwanted effects. Use of herbal products and potential interactions in patients with cardiovascular diseases. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. The extended-release tablet usually is taken once daily in the morning. Cardizem Alternatives Compared - Drugs.com Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. Natural Medicines. This document does not contain all possible drug interactions. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . Do not double the dose to catch up. It can make you really dizzy. https://naturalmedicines.therapeuticresearch.com. If you have recently had a head injury or a heart attack. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). This content does not have an English version. Am J Ther. Isosorbide controls chest pain but does not cure coronary artery disease. We comply with the HONcode standard for trustworthy health information. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. [2] This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. https://naturalmedicines.therapeuticresearch.com. Please enable it to take advantage of the complete set of features! Side effects : headache, mild dizziness This site complies with the HONcode standard for trustworthy health information: verify here. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. You need to take it every day in order for it to work. Isosorbide mononitrate dose and side-effects info | Patient Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Isosorbide mononitrate Alternatives Compared - Drugs.com A very serious allergic reaction to this drug is rare. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. Isosorbide is in a class of medications called vasodilators. A single copy of these materials may be reprinted for noncommercial personal use only. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. Things to remember when you fill your prescription. It is unknown if this medication passes into breast milk. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Integrative medicine (complementary and alternative medicine). Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. The information on this page is written and peer reviewed by qualified clinicians. Consult your pharmacist or local waste disposal company. Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Accessed Sept. 7, 2022. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. This does not necessarily mean no interactions exist. Elsevier; 2021. https://www.clinicalkey.com. During pregnancy, this medication should be used only when clearly needed. What special precautions should I follow? Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Zhonghua Yi Xue Za Zhi (Taipei). Let your provider know if they are excessive. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma https://www.uptodate.com/contents/search. Herbal medications in cardiovascular medicine. Accessed Sept. 7, 2022. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Keep all medicines out of the reach and sight of children. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. If we combine this information with your protected To view a report comparing 3 (or more) medications, please sign in or create an account. Using this medicine with any of the following medicines is not recommended. Nitrates in the management of acute coronary syndrome. Accessed Sept. 7, 2022. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. It has a very short duration of action and may not be suitable for some people. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Natural Medicines. Accessed Sept. 7, 2022. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Who should not take Isosorbide Mononitrate? Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. May also be prescribed off label for Esophageal Spasm. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. http://www.upandaway.org. It is in the nitrate class of drugs. St. Joseph 81 mg Aspirin Enteric Safety-Coated. What side effects can this medication cause? Prices for isosorbide mononitrate (Monoket) start at just $29.86 with a GoodRx coupon. Seek alternatives to the CYP3A4 substrate when possible. Canada residents can call a provincial poison control center. The narrowing makes it more difficult for blood to flow to your heart muscle. If you have an eye condition called glaucoma. Prescribed for Angina, Anal Fissure and 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Registered in England and Wales. isosorbide mononitrate (Imdur, Ismo, Monoket) - MedicineNet 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. This should pass after a few days. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Isosorbide mononitrate belongs to the group of medicines called nitrates. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Dehydration in Buspar, how severe and when it was recovered? For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. My EKG showed Assess your symptoms online with our free symptom checker. 2005 - 2023 WebMD LLC. It might help to keep the room cool and use a fan. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. Thirty percent of the patients never experienced headache from the given dosages. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Isosorbide mononitrate systemic 60 mg (A ID). Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). sharing sensitive information, make sure youre on a federal Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Ask your doctor before using aspirin together with alcohol. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. This is called tolerance, and it cannot be fixed by raising the dose of the medication. Isosorbide: MedlinePlus Drug Information Do not let anyone else take your medication. isosorbide mononitrate prices. Please upgrade your browser or download modern browsers from here! What are the interactions of Isosorbide Mononitrate ? These side effects may go away during treatment as your body adjusts to the medicine. Learn to reduce stress through mindful living. This risk may be even higher for certain groups. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. https://naturalmedicines.therapeuticresearch.com. Isosorbide Mononitrate - Uses, Side Effects, Substitutes, Composition We study 23,548 Isosorbide mononitrate users. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Drug interactions may change how your medications work or increase your risk for serious side effects. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. View all This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". Do not take two doses together to make up for a missed dose. Do not stop taking it without consulting your doctor. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Take the container with you, even if it is empty. Isosorbide mononitrate Interactions - Drugs.com It is important that you follow the instructions your doctor gives to you about when to take your doses. Take isosorbide exactly as directed. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Advertising revenue supports our not-for-profit mission. Isosorbide mononitrate (Monoket) can cause some serious health issues. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. It is best not to drink alcohol while you are on isosorbide mononitrate. Dated October 2016. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. All rights reserved. Although not all of these side effects may occur, if they do occur they may need medical attention. Natural Medicines. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. I took this for 4 days, and my headaches were unbearable. official website and that any information you provide is encrypted Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). This content does not have an Arabic version. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Unless your doctor tells you otherwise, continue your normal diet. It is also important information to carry with you in case of emergencies. Mayo Clinic does not endorse companies or products. Some of these medicine interactions can be risky. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. To use the sharing features on this page, please enable JavaScript. This should pass after a few days. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. In case of overdose, call the poison control helpline at 1-800-222-1222. Isosorbide mononitrate has an average rating of Do not share this medication with others. But only about 25% of people who take herbal supplements tell their health care providers. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Diabetes treatment: Can cinnamon lower blood sugar? Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. The table below contains some of the most common ones associated with isosorbide mononitrate. Eur Heart J. Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Some of these interactions can be life-threatening. The IR version can help treat and prevent angina. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Unable to load your collection due to an error, Unable to load your delegates due to an error. If it is within 2 hours of the next dose, skip the missed dose. This medicine is available only with your doctor's prescription. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. You may report side effects to the FDA at 1-800-FDA-1088. government site. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). See also: aspirin side effects in more detail. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Do not start, stop, or change the dosage of any medicines without your doctor's approval. The dose is according to the body weight and severity of the condition. Please see a good cardiologist, get admitted, get checked thoroughly. List of Antianginal agents (antianginal drugs) - Drugs.com Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. View interaction reports for isosorbide mononitrate and the medicines listed below. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). All rights reserved. Before It can cause your blood pressure to become dangerously low. Take extra precautions to avoid falling during your treatment with isosorbide. Ask your pharmacist any questions you have about refilling your prescription. Follow directions about how much medicine to take. Take the missed dose as soon as you remember it. Nitrates | Prescribing information | Angina | CKS | NICE Some don't work well with prescription medicines. Many people using this medication do not have serious side effects. This is called a medicine interaction. Duplication for commercial use must be authorized by ASHP. Accessed Sept. 7, 2022. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Cardizem may also be used for purposes not listed in this medication guide. Do not stop taking isosorbide without talking to your doctor. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. Isosorbide dinitrate (Isordil): Basics, Side Effects & Reviews - GoodRx Isosorbide mononitrate - Wikipedia 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. It will not treat an angina attack that has already begun. https://naturalmedicines.therapeuticresearch.com. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Results: Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. It works to relax your blood vessels. These side effects may go away during treatment as your body adjusts to the medicine. https://naturalmedicines.therapeuticresearch.com. Real test is coronary angiography. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. Isosorbide mononitrate belongs to the group of medicines called nitrates. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Generic alternatives may be available. Minimally clinically significant. B complex. Isosorbide - StatPearls - NCBI Bookshelf 2023 Lybrate, Inc. All rights reserved. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. AskMayoExpert. Journal of the American College of Cardiology. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. . Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Is not subject to the Controlled Substances Act. Herbal supplements and heart medicines may not mix - Mayo Clinic 8600 Rockville Pike Mayo Clinic. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Headache and weakness of left side (both arm and leg) may suggest a brain pathology.